Orlistat is the only medicine currently licensed in the EU to help you lose weight. Orlistat prevents your body from absorbing the fat from the food you eat. By reducing the amount of fat that is absorbed, Orlistat is clinically proven to help you lose up to 50% more weight than with dieting alone. Generic medicines contain the same active ingredient and are equally effective and medically equivalent as the branded products but are available at a lower price. Generic manufacturers have to demonstrate that they are medically identical to the branded product - i.e. they offer the same quality, strength, stability and effectiveness. Visit our Generic Medicine FAQ for more information Orlistat 120mg is used in the treatment of obesity. If you're trying to lose weight, you might consider a diet pill like Xenical or alli. Both weight loss aids contain the same medication, called orlistat, but in different amounts. Xenical is the prescription dose (120 mg) of orlistat. Xenical is approved by the Food and Drug Administration and intended to be used by individuals with a body mass index (BMI) of 30 or more or a BMI of 27 along with a weight-related condition like type 2 diabetes or hypertension. Xenical can also be used for people who have lost weight and want to prevent weight regain. Xenical is designed to be used along with a low-fat, low-calorie diet. Those who lose weight with the medication are more likely to be successful over the long-term and keep the weight off for good if they follow a healthy lifestyle. This type of medication is called a lipase inhibitor because it helps your body to absorb less fat from the food that you eat. 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