Osteopenia is a bone condition characterized by a decreased density of bone, which leads to bone weakening and an increased risk of breaking a bone (fracture). Osteopenia and osteoporosis are related conditions. The difference between osteopenia and osteoporosis is that in osteopenia the bone loss is not as severe as in osteoporosis. This means that someone with osteopenia is more likely to fracture a bone than someone with a normal bone density but is less likely to fracture a bone than someone with osteoporosis. The condition is common in patients with syndromes such as ankylosing spondylitis, rheumatoid arthritis, psoriasis, pemphigus vulgarism, systemic lupus erythematosus, multiple sclerosis, and inflammatory bowel diseases. Multiple sclerosis (MS) is a chronic inflammatory disease affecting the brain and spinal cord, leading to muscle weakness, coordination and balance problems, as well as sensation disorders, visual and cognitive deficits, and gradual limitation of functioning. Subjects with MS have multiple risk factors for osteopenia. In the pathological lesion of the brain and spinal cord that characterizes MS, there are differences in the disease according to the evolution of the lesion (i.e., progressive MS vs relapsing remitting), including residual mobility and functionality, the ability to walk and stand, and drug treatment (i.e., corticosteroid therapy, interferon therapy). Doctors may not always keep up with the latest research on drug side effects. A busy family practice physician, internist or OB/GYN may have to see more than 20 patients a day. By the end of an exhausting workday overseeing so many patients, there is not a lot of time or energy left to review the medical literature. Unfortunately, however, that can put patients at risk. The following question reveals what can happen when two popular drugs are prescribed together. I went to my doctor with menopausal symptoms of flushing, dizziness, queasiness and headaches. He prescribed an antidepressant called sertraline that made the queasiness worse. The sertraline has made me scatterbrained and fatigued. I hate taking so many drugs and wonder if there is another option to help me get through menopause. We are concerned about the combination of the antidepressant sertraline (Zoloft) and the acid suppressor omeprazole. Research suggests that both drugs can contribute to weakened bones, a significant hazard after menopause. Levitra trial Where can i order accutane online Mar 2, 2018. Certain drugs increase your risk for osteoporosis or spinal fracture—What you need. Fluoxetine Prozac; Paroxetine Paxil; Sertraline Zoloft. I guess Zoloft stays in your system longer than Paxil. I have been on Zoloft before for several years off and on, usually between 50 and 100 mgs, but have stopped taking it for about 3 months. I have not suffered from any withdrawal symptoms. Osteoporosis is a bone disease that occurs when the body loses too much bone, makes too little bone, or both. As a result, bones become weak and may break from a fall or, in serious cases, from sneezing or minor bumps. Medications can be a double-edged sword—they can be vital when it comes to treatment of a specific condition, but they can introduce other problems. For example, did you know that several drug classes can interfere with bone health? If you’re a long-term user of one of the medications below, you may be putting yourself at risk for osteoporosis and/or spinal fracture. This article describes drugs that are potentially bad for your bones and how you can protect yourself. While not all the medications listed treat spine disorders or neck and back pain, you may take one or more of these drugs for other medical conditions. : Oral steroids (which are taken by mouth) are commonly prescribed for spinal conditions, including low back pain, neck pain, and spinal inflammatory arthritis. These drugs contain powerful anti-inflammatory medication, which may help ease pain but can cause bone loss with long-term use. If you're a middle-aged woman, boosting your mood could cost you your bones. In a recent observational study, researchers found that women aged 40 to 64 who took antidepressants—specifically, selective serotonin reuptake inhibitors (SSRIs)—to cool off the hot flashes and night sweats of perimenopause were up to 76% more likely to break a bone. The risk was 73% after 2 years and 67% after 5 years. Get your FREE trial of , Sheu and his team looked at health data from the Phar Metrics Claims Database, focusing on some 137,000 women with no mental health issues who started SSRIs between 19. (Check out these ways to help make menopause less miserable.) "Elevated fracture risk can be observed after just 6 months on the antidepressants and stays stably elevated for the next 5 years," says lead investigator Yi-han Sheu, MD, a doctoral student in the department of epidemiology at Harvard University's T. The SSRIs included citalopram, escitalopram, fluoxetine, fluvoxamine paroxetine, and sertraline, better known as Celexa, Paxil, Prozac, and Zoloft. They then compared the bone strength of this group over a 5-year period with that of a control group of 236,000 women of the same age who were taking medication for indigestion. "The risk of fracture among those who took SSRIs was about 1.7 times higher than among those who were treated with indigestion drugs," Sheu says. MORE: 7 Odd Reasons You Bruise Easily It's well established that fracture risk is higher among SSRI users with mental disorders such as depression, which is why Sheu and his team purposely looked at women who were taking SSRIs for non-psychiatric reasons—in this case, to manage the vasomotor symptoms of menopause. The goal was to see if taking SSRIs would also weaken bones in the absence of psychiatric conditions. "While we chose middle-aged women who were prone to menopausal symptoms as our population, this effect is not confined to those with menopausal symptoms," Sheu explains. Zoloft osteoporosis Bone Loss, Osteopenia and Multiple Sclerosis, Paxil and osteoporosis - MedHelp Buy flagyl ukCiprofloxacin erectile dysfunctionMerotexato 7,5 mgAzithromycin sinus infectionZithromax oral suspension pediatric dosage How are depression and osteoporosis linked? studies show that older people with depression are more. Zoloft, and fluoxetine prozac Depression and Osteoporosis - NIMH. Learn What Osteoporosis Is and What It’s Caused by -. Drug Interaction Could Lead to Disastrous Osteoporosis and Bone.. Understanding the link between mammary tissue, and its bone mass density loss that can lead to osteoporosis Researchers at the University of Cincinnati recently have published research identifying the neurotransmitter, serotonin as a factor in bone mass density loss/retention. Some medications prescribed for common health problems, such as heartburn or depression. National Osteoporosis Foundation "Medicines Approved to Prevent and/or Treat Osteoporosis." Sep 5, 2016. Some antidepressants have been linked to an increased risk of bone fractures. It now seems that fluoxetine – the compound in Prozac.